Transgenic & knock-in mouse models

Sequencing tools & datasets

I. Sample enrichment for single-nucleus sequencing using concanavalin A-conjugated magnetic beads

Note: mice shown in gray are not currently available in the lab. Please contact us for additional information.

STAR Protoc. 2023;4(4):102595. PubMed PMID: 37740915. PDF

II. Bulk, single-nucleus, and multiome analyses of developing and adult mouse hypothalamic neurons

• Comparative transcriptomic analyses of developing POMC and NPY/AgRP neurons in E15.5 mouse embryos

J Neurosci. 2020;40(16). PubMed PMID: 32213554. PDF

• Hypothalamic gene expression signature associated with chronic risperidone treatment in C57BL/6 mice

J Exp Med. 2021;218(7). PubMed PMID: 33978701. PDF

• Single-nucleus RNA-seq analysis of adult AgRP-Cre neurons in the arcuate nucleus of C57BL/6 mice

J Exp Med. 2022;219(8). PubMed PMID: 35796804. PDF

• Bulk RNA-seq analysis of hypothalamic MC4R-Cre neurons in adult C57BL/6 mice

Sci Transl Med. 2025;17(781). PubMed PMID:39813316. PDF

• Single-nucleus RNA-seq analysis of Sim1-Cre neurons in the paraventricular nucleus of the hypothalamus

Sci Transl Med. 2025;17(781). PubMed PMID:39813316. PDF

• Single-nuclei multiome analyses of POMC-derived neurons in the adult mouse mediobasal hypothalamus

Neuron 2026;114(1210). PubMed PMID: 41702397 PDF

Open-source diets for modeling antipsychotic drug–induced metabolic syndrome in female mice

• A rodent diet for modeling olanzapine-induced metabolic syndrome

J Clin Invest. 2017;127(9). PubMed PMID: 28805659. PDF

• A rodent diet for modeling risperidone-induced metabolic syndrome

J Exp Med. 2021;218(7). PubMed PMID: 33978701. PDF

• A rodent diet for modeling clozapine-induced metabolic syndrome

bioRxiv. 2024.06.07.597981 2019:753434. PDF

Note: all reported diets are fully open source and can be purchased directly from Research Diets.